An elephant never forgets … its proper cell structures. Big organisms need these cancer countermeasures. Too many cells = too high a probability of cancer. Interesting. But P53 doesn’t “hunt” for tumors. It is Awesome Elephant Piss Me Off I Will Slap You So Hard Even Google Won’t Be Able To Find You Shirt a tumor suppressor because it is central in cell cycle regulation (mitosis). One reason is that it is part of a class of genes known as transcription factors, meaning it is involved in the gene regulation of other genes (and subsequent mRNA and protein abundance) of a large number of tumor promoters. Things like EGFR and VEGF and so forth.
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But it’s more complicated than that because some drugs downregulate (act as an agonist) P53, yet suppress tumors through some other pathway like calcium signaling for Awesome Elephant Piss Me Off I Will Slap You So Hard Even Google Won’t Be Able To Find You Shirt example which regulates cell migration and invasion. Facebook, Twitter, Instagram, TikTok… none of the other big names has this. Thank you and thanks for letting me have my moment. I’m sure some downvotes or snarky comments will remind me that I’m still in a social media cesspool. I check the news subs every day, but I am not subscribed to them. Too much negativity to see plastered all over my front page.
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